Data
Year of publication
2020
Type
Qualitative
Design
Narrative
Classification
Other (non-stated)
Country studied
Global
Data
Secondary
Data Collected
Literature
Study setting
Online
Age group of participant
N/A
Participant sex
N/A
Target population
General
Sample size
N/A
Food additives containing nanoparticles induce gastrotoxicity, hepatotoxicity and alterations in animal behavior: The unknown role of oxidative stress
Goal
Analyze the evidence of gastrotoxicity, hepatotoxicity and the impact of microbiota on gut-brain and gut-liver axis induced by titanium dioxide (E171), iron oxides and hydroxides (E172), silver (E174), and gold (E175) are highly used as colorants while silicon dioxide (E551) and their non-food grade nanosized counterparts after oral consumption.
Results
These food additives induce gastrotoxicity, hepatotoxicity and alterations in gut microbiota and most evidence points out oxidative stress as the main mechanism of toxicity, however, the role of oxidative stress as the main mechanism needs to be explored further.
Authors
Medina-Reyes EI, Rodríguex-Ibarra C, Déciga-Alcaraz A, Diaz-Urbina D, Chirino YI, Pedraza-Chaverri J.
Journal
Food and Chemical Toxicology
DOI